4/05/2010

A race to erase polio

A race to erase polio text describing the image


Runners hit the streets during the Milton Rotary Club’s first 5k race, held two years ago in the Milton State Park. The third annual Milton Rotary 5K run/walk at the Milton State Park is slated for 9 a.m. Saturday, April 10. Registration is $15 before April 1. For more information, e-mail Chris Brady atcbrady@windstream.net. Standard Journal file photo.

Annual event is April 10 at Milton State Park

By Kevin Mertz
Published:
Saturday, March 27, 2010 3:11 AM CDT
MILTON — Runners and walkers, it’s almost time to lace up your sneakers for a good cause.

The third annual Milton Rotary 5K run/walk at the Milton State Park is slated to step off at 9 a.m. Saturday, April 10.

Runners and walkers will begin and end their events at the Milton State Park.

“It is dubbed the race to erase polio, because all the proceeds go to Rotary International’s goal of erasing polio from the planet,” said Chris Brady, event chair. “Polio is not at the forefront of diseases here in America, but it is a crippling disease that has, and continues to, afflict so many people.”


There are plenty of individuals who know people who have been affected by the disease, he said.

“Knowing that Rotary International is this close to wiping it out, every little bit helps,” Brady said.

He noted this is the first year that a walk will part of the event.

“We felt that, by adding a walk, it would allow a lot of people that wouldn’t otherwise participate to have the opportunity to take part in the event,” Brady said. “Plus it’s a great way to showcase the work that’s been done by the Friends of the Milton State Park.”

He said the walk will take place entirely within the park and will cover the trails Friends of the Milton State Park have been working hard to maintain.

“With the trails they created on the south portion of the island, you get a scenic view of the river and they’re really well maintained,” Brady continued. “If you’re lucky, you even get to see wildlife (while walking the trails).”


He said walkers may choose the distance they wish to cover. Distances begin at a half mile and go up from there. For the 5K race, which starts on the island, then continues into Milton before ending back on the island, Brady said support from the borough of Milton has been outstanding.

“We are deeply indebted to the borough, Chief (Craig) Lutcher and his police force in helping to ensure the runners’ safety on the roads,” Brady said. He noted the fire police also play a key role in protecting the participants during the event.

He also praised his fellow Rotarians who give their time to help make the event a success.

“A large portion of the club volunteers for this in one form or another,” Brady said.

He said the overall winning runners will receive a trophy.

“We have medals for (select) finishers,” he continued. “All pre-registered runners and walkers get a free T-shirt.”

A limited number of T-shirts will be available for runners registering on race day.

Registration is $15 before April 1, $20 on race day. Registration forms are available at the TIME office, Standard Journal or by e-mailing cbrady@windstream.net.

Staff writer Kevin Mertz can be reached at 570-742-9671 or e-mail kevin@standard-journal.com.



Hacer un Amigo es una Gracia
Tener un amigo es un Don
Conservar un Amigo es una Virtud
Ser un Amigo es un Honor




















The Polio Crusade

THE POLIO CRUSADE IN AMERICAN EXPERIENCE A GOOD VIDEO THE STORY OF THE POLIO CRUSADE pays tribute to a time when Americans banded together to conquer a terrible disease. The medical breakthrough saved countless lives and had a pervasive impact on American philanthropy that ... Continue reading..http://www.pbs.org/wgbh/americanexperience/polio/

Erradicación de La poliomielitis

Polio Tricisilla Adaptada

March Of Dimes Polio History

Dr. Bruno

video

movie

movie2

A 41-year-old man developed an acute illness at the age of 9 months during which, following a viral illness with headache, he developed severe weakness and wasting of the limbs of the left side. After several months he began to recover, such that he was able to walk at the age of 2 years and later was able to run, although he was never very good at sports. He had stable function until the age of 18 when he began to notice greater than usual difficulty lifting heavy objects. By the age of 25 he was noticing progressive difficulty walking due to weakness of both legs, and he noticed that the right calf had become larger. The symptoms became more noticeable over the course of the next 10 years and ultimately both upper as well as both lower limbs had become noticeably weaker.

On examination there was wasting of the muscles of upper and lower limbs on the left, and massively hypertrophied gastrocnemius, soleus and tensor fascia late on the right. The calf circumference on the right exceeded that on the left by 10 cm (figure1). The right shoulder girdle, triceps, thenar eminence and small muscles of the hand were wasted and there was winging of both scapulae. The right quadriceps was also wasted. The wasted muscles were also weak but the hypertrophied right ankle plantar flexors had normal power. The tendon reflexes were absent in the lower limbs and present in the upper limbs, although the right triceps was reduced. The remainder of the examination was normal.

Figure 1

The patient's legs, showing massive enlargement of the right calf and wasting on the left

Questions

1
What is that nature of the acute illness in infancy?
2
What is the nature of the subsequent deterioration?
3
What investigations should be performed?
4
What is the differential diagnosis of the cause of the progressive calf hypertrophy?

Answers

QUESTION 1

An acute paralytic illness which follows symptoms of a viral infection with or without signs of meningitis is typical of poliomyelitis. Usually caused by one of the three polio viruses, it may also occur following vaccination and following infections with other enteroviruses.1 Other disorders which would cause a similar syndrome but with upper motor neurone signs would include acute vascular lesions, meningoencephalitis and acute disseminated encephalomyelitis.

QUESTION 2

A progressive functional deterioration many years after paralytic poliomyelitis is well known, although its pathogenesis is not fully understood.2 It is a diagnosis of exclusion; a careful search for alternative causes, for example, orthopaedic deformities such as osteoarthritis or worsening scoliosis, superimposed neurological disorders such as entrapment neuropathies or coincidental muscle disease or neuropathy, and general medical causes such as respiratory complications and endocrinopathies.3

QUESTION 3

Investigations revealed normal blood count and erythrocyte sedimentation rate and normal biochemistry apart from a raised creatine kinase at 330 IU/l (normal range 60–120 IU/l), which is commonly seen in cases of ongoing denervation. Electromyography showed evidence of denervation in the right APB and FDI with polyphasic motor units and complex repetitive discharges, no spontaneous activity in the left calf and large polyphasic units in the right calf consistent with chronic partial denervation. Motor and sensory conduction velocities were normal. A lumbar myelogram was normal. Magnetic resonance imaging (MRI) scan of the calves is shown in figure2.

Figure 2

Axial T1 weighted MRI scan (TR 588 ms, TE 15 ms) of the calves, showing gross muscle atrophy and replacement by adipose tissue on the left, and hypertrophy of the muscles on the right, with only minor adipose tissue deposition

QUESTION 4

The differential diagnosis of the progressive calf hypertrophy is given in the box.

Causes of calf muscle hypertrophy

Chronic partial denervation

  • radiculopathy

  • peripheral neuropathy

  • hereditary motor and sensory neuropathy

  • spinal muscular atrophy

  • following paralytic poliomyelitis

    Neuromyotonia and myokymia

  • Isaac's syndrome

  • generalised myokymia

  • neurotonia

  • continuous muscle fibre activity due to: chronic inflammatory demyelinating polyradiculopathy, Guillain Barre syndrome, myasthenia gravis, thymoma, thyrotoxicosis, thyroiditis

    Muscular dystrophies

    Myositis

    Infiltration

  • tumours

  • amyloidosis

  • cysticercosis

    Link here